Research on noble metal nanoparticles (NPs) able to scavenge reactive oxygen species (ROS) has undergone a tremendous growth recently. However, the interactions between ruthenium nanoparticles (Ru NPs) and ROS have never been systematically explored thus far. This research focused on the decomposition of hydrogen peroxide (H2O2), scavenging of hydroxyl radicals (•OH), superoxide radical (O2•-), singlet oxygen (1O2), 2,2'-azino-bis(3-ethylbenzenothiazoline- 6-sulfonic acid ion (ABTS•+), and 1,1-diphenyl-2-picrylhydrazyl radical (•DPPH) in the presence of commercial Ru NPs using the electron spin resonance technique. In vitro cell studies demonstrated that Ru NPs have excellent biocompatibility and exert a cytoprotective effect against oxidative stress. These findings may spark fresh enthusiasm for the applications of Ru NPs under relevant physiologically conditions.

中文翻译：

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探索钌纳米材料作为活性氧清除剂的活性。

能够清除活性氧（ROS）的贵金属纳米颗粒（NPs）的研究最近得到了极大的发展。但是，到目前为止，尚未系统地研究钌纳米颗粒（Ru NPs）与ROS之间的相互作用。这项研究的重点是过氧化氢（H2O2）的分解，清除羟自由基（•OH），超氧自由基（O2•-），单线态氧（1O2），2,2'-叠氮基双（3-乙基苯并噻唑啉）-6电子自旋共振技术在商业化Ru NPs存在下，检测到-磺酸离子（ABTS•+）和1,1-二苯基-2-甲基苯并肼基（•DPPH），体外细胞研究表明Ru NPs具有出色的生物相容性并发挥抗氧化应激的细胞保护作用。