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Update on Actinomucor elegans, a mucormycete infrequently detected in human specimens: how combined microbiological tools contribute efficiently to a more accurate medical care.
International Journal of Medical Microbiology ( IF 4.5 ) Pub Date : 2017-11-08 , DOI: 10.1016/j.ijmm.2017.10.010
J Dorin 1 , M D'Aveni 2 , A Debourgogne 1 , M Cuenin 2 , M Guillaso 3 , A Rivier 3 , P Gallet 4 , G Lecoanet 5 , M Machouart 1
Affiliation  

Actinomucor elegans is a fungus belonging to mucormycetes and is still probably underdiagnosed due to misidentification. Based on a recent first case of Actinomucor elegans sinusitis in Europe, in an immunocompromised patient under voriconazole treatment, this paper aims to summarize knowledge about A. elegans mucormycoses. Even if the diagnosis of mucormycosis was made using traditional mycology techniques, precise identification of the fungus could only be achieved using molecular tools. In this observation, the galactomannan dosage was positive until the introduction of treatment and surgical debridement. The patient experienced no relapse after one year. By reviewing the four previous A. elegans reported cases and describing the mycological characteristics of this species, we highlight the need to use a combination of tools to improve the diagnostic strategy in such rare and life-threatening clinical situations.

中文翻译:

线虫放线杆菌(Actinomucor elegans)的更新,这种放线菌在人体标本中很少发现:组合的微生物工具如何有效地促进更准确的医疗。

线虫放线杆菌(Actinomucor elegans)是一种属于粘液菌的真菌,由于识别错误,可能仍未得到充分诊断。基于欧洲最近发生的线虫放线杆菌鼻窦炎的第一例,在伏立康唑治疗的免疫功能低下患者中,本文旨在总结关于线虫放线杆菌的知识。即使使用传统的真菌学技术对毛霉菌病进行诊断,也只能使用分子工具来准确鉴定真菌。在此观察中,半乳甘露聚糖剂量为阳性,直到引入治疗和手术清创术为止。一年后患者没有复发。通过回顾先前报道的四条线虫病例并描述该物种的真菌学特征,
更新日期:2019-11-01
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