The Pauson-Khand [2+2+1] cycloaddition of alkynes, alkenes, and carbon monoxide has been a vibrant area of research for more than 40 years. This review highlights recent achievements in the Pauson-Khand reaction, particularly in catalytic and asymmetric variants. Discussion of regioselectivity and advances in substrate scope is also presented.

中文翻译：

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Pauson-Khand反应的最新进展。

40多年来，炔烃，烯烃和一氧化碳的Pauson-Khand [2 + 2 + 1]环加成一直是一个充满活力的研究领域。这篇综述着重介绍了Pauson-Khand反应的最新成就，特别是在催化和不对称变体方面。还讨论了区域选择性和底物范围的进展。