Transcatheter aortic valve replacement (TAVR) is a safe and effective therapy for aortic valve replacement in patients ineligible for or at high risk for surgery. However, outcomes after TAVR based on an individual's sex remain to be fully elucidated. We searched PUBMED and EMBASE using the keywords: "transcatheter aortic valve replacement," "transcatheter aortic valve implantation," "sex differences," "gender," "sex characteristics" and collected information on baseline features, procedural characteristics, and postprocedural outcomes in women. Inclusion/exclusion resulted in 23 publications. Women had less preexisting comorbidities than men. Most studies reported better survival in women (range of hazard ratio [95% CI] = 0.27 [0.09-0.84] to 0.91 [0.75-1.10]). At 30 days, women also had more vascular complications (6-20% vs 2-14%) and higher bleeding rates (10-44% vs 8-25%). Stroke rates were similar at 30 days (women, 1-7%; men, 1-5%). This literature review showed better survival in women than men after TAVR. However, women had more vascular complications and bleeding; stroke rates were similar. These findings may partly be explained by fewer baseline comorbidities in women. These results should be interpreted with caution as most measures only include unadjusted percentages.

中文翻译：

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经导管主动脉瓣置换后的特定性别结局：文献综述。

经导管主动脉瓣置换术（TAVR）是对不适合手术或处于高手术风险中的患者进行主动脉瓣置换的安全有效治疗。然而，基于个体性别的TAVR后的结局仍有待充分阐明。我们使用以下关键词搜索了PUBMED和EMBASE：“经导管主动脉瓣置换术”，“经导管主动脉瓣植入术”，“性别差异”，“性别”，“性别特征”，并收集了有关基线特征，手术特征和手术后结果的信息女性。纳入/排除导致23出版物。妇女的合并症少于男性。大多数研究报告说女性生存率更高（危险率[95％CI] = 0.27 [0.09-0.84]至0.91 [0.75-1.10]）。在30天后，女性的血管并发症也更多（6-20％比2-14％）和更高的出血率（10-44％比8-25％）。30天的中风发生率相似（女性为1-7％；男性为1-5％）。这篇文献综述显示，TAVR后女性的生存率高于男性。但是，女性的血管并发症和出血更多。中风发生率相似。这些发现可能部分是由于女性基线合并症较少。对这些结果的解释应谨慎，因为大多数措施仅包括未调整的百分比。这些发现可能部分是由于女性基线合并症较少。对这些结果的解释应谨慎，因为大多数度量仅包括未调整的百分比。这些发现可能部分是由于女性基线合并症较少。对这些结果的解释应谨慎，因为大多数措施仅包括未调整的百分比。