Abstract This paper focuses on the development of the hydroxylamine phosphate oxime (HPO) process for the manufacture of caprolactam, an intermediate for nylon, by Central Laboratory, the R&D organisation of the Dutch chemical company DSM. The example of the HPO process shows that Central Laboratory was independent rather than isolated. This position enabled it to develop its own view of the interest of the company and start research projects regardless of the opinion of the production and marketing functions. The example of the HPO process shows the potency of such a position but also the problems involved. As a medium-sized chemical company, DSM is a company that may be more typical for the practice of R&D between 1945 and 1970 than the large companies that historians have typically chosen for analysis.

中文翻译：

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工业研究作为“企业反文化”？DSM 的 HPO 己内酰胺工艺的开发，1956-77

摘要 本文重点介绍了由荷兰化学公司 DSM 的研发机构中央实验室开发的羟胺磷酸肟 (HPO) 工艺，用于生产尼龙中间体己内酰胺。HPO 流程的例子表明，中心实验室是独立的，而不是孤立的。这一职位使其能够根据公司利益制定自己的观点，并开始研究项目，而不管生产和营销职能部门的意见如何。HPO 流程的示例显示了这种职位的效力，但也显示了所涉及的问题。作为一家中型化工公司，与历史学家通常选择进行分析的大公司相比，帝斯曼可能是一家在 1945 年至 1970 年间进行研发实践的公司。