The decipherment of the tRNA's operational code, known as the identity problem, requires the location of the sites in the tRNA structure that are involved in their correct recognition by the corresponding aminoacyl-tRNA synthetase. In this work, we determine the identity elements of each tRNA isoacceptor by means of the variation of information measure from information theory. We show that all isoacceptors exhibit sites associated with some bases of the anticodon. These sites form clusters that are scattered along the tRNA structure. The clusters determine the identity elements of each tRNA. We derive a catalogue of clustered sites for each tRNA that expands previously reported elements.

中文翻译：

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来自信息分析的tRNA身份元素。

解密tRNA的操作代码（称为身份问题）需要在tRNA结构中定位与相应的氨酰基tRNA合成酶正确识别有关的位点。在这项工作中，我们通过信息理论中信息量度的变化来确定每个tRNA异构受体的身份元素。我们表明，所有的isoacceptors展示与反密码子的一些碱基相关的网站。这些位点形成沿tRNA结构分散的簇。簇确定每个tRNA的身份元件。我们为每个tRNA导出了一个聚簇位点目录，该目录扩展了先前报道的元素。