Studying the strategies of improving abiotic stress tolerance is quite imperative and research under this field will increase our understanding of response mechanisms to abiotic stress such as heat. The Hsp70 is an essential regulator of protein having the tendency to maintain internal cell stability like proper folding protein and breakdown of unfolded proteins. Hsp70 holds together protein substrates to help in movement, regulation, and prevent aggregation under physical and or chemical pressure. However, this review reports the molecular mechanism of heat shock protein 70 kDa (Hsp70) action and its structural and functional analysis, research progress on the interaction of Hsp70 with other proteins and their interaction mechanisms as well as the involvement of Hsp70 in abiotic stress responses as an adaptive defense mechanism.

研究提高非生物胁迫耐受性的策略是当务之急，该领域的研究将使我们加深对非生物胁迫（例如热）的响应机制的了解。Hsp70是必需的蛋白质调节剂，具有维持内部细胞稳定性（如正确折叠的蛋白质和未折叠的蛋白质分解）的趋势。Hsp70将蛋白质底物结合在一起，以帮助其在物理和/或化学压力下运动，调节并防止聚集。然而，本综述报道了热休克蛋白70 kDa（Hsp70）作用的分子机理及其结构和功能分析，Hsp70与其他蛋白的相互作用及其相互作用机理的研究进展，以及Hsp70参与非生物胁迫反应的研究进展。作为一种自适应防御机制。