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Injectable scaffolds: Preparation and application in dental and craniofacial regeneration.
Materials Science and Engineering: R: Reports ( IF 31.6 ) Pub Date : 2017-01-01 , DOI: 10.1016/j.mser.2016.11.001
Bei Chang 1 , Neelam Ahuja 1 , Chi Ma 1 , Xiaohua Liu 1
Affiliation  

Injectable scaffolds are appealing for tissue regeneration because they offer many advantages over pre-formed scaffolds. This article provides a comprehensive review of the injectable scaffolds currently being investigated for dental and craniofacial tissue regeneration. First, we provide an overview of injectable scaffolding materials, including natural, synthetic, and composite biomaterials. Next, we discuss a variety of characteristic parameters and gelation mechanisms of the injectable scaffolds. The advanced injectable scaffolding systems developed in recent years are then illustrated. Furthermore, we summarize the applications of the injectable scaffolds for the regeneration of dental and craniofacial tissues that include pulp, dentin, periodontal ligament, temporomandibular joint, and alveolar bone. Finally, our perspectives on the injectable scaffolds for dental and craniofacial tissue regeneration are offered as signposts for the future advancement of this field.

中文翻译:

可注射支架:制备及其在牙科和颅面再生中的应用。

可注射支架对于组织再生很有吸引力,因为它们比预成型支架具有许多优点。本文对目前正在研究的用于牙科和颅面组织再生的可注射支架进行了全面综述。首先,我们概述了可注射支架材料,包括天然、合成和复合生物材料。接下来,我们讨论可注射支架的各种特征参数和凝胶机制。然后介绍了近年来开发的先进的注射脚手架系统。此外,我们总结了可注射支架在牙髓、牙本质、牙周膜、颞下颌关节和牙槽骨等牙齿和颅面组织再生中的应用。最后,我们对用于牙科和颅面组织再生的可注射支架的看法作为该领域未来发展的路标。
更新日期:2019-11-01
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