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Vigor of survival determinism: subtle evolutionary gradualism interspersed with robust phylogenetic leaping.
Theory in Biosciences ( IF 1.3 ) Pub Date : 2017-06-19 , DOI: 10.1007/s12064-017-0251-4
Pavle Krsmanovic 1
Affiliation  

Discussions of the survival determinism concept have previously focused on its primary role in the evolution of early unicellular organisms in the light of findings which have been reported on a number of diseases. The rationale for such parallel was in the view according to which multicellular organisms could be regarded as sophisticated colonies of semi-autonomous, single-celled entities, whereby various diseases were described as conditions arising upon the activation of the respective survival mechanisms in a milieu unsuitable for such robust stress response. The cellular mechanisms that were discussed in these contexts have been known to play various roles in other biological processes. The proposed notion could thereby be further extended to discussion on mechanisms for the implementation of the respective survival pathways in the development of metazoa, considering that they would have been propagated in their evolution for so long. This manuscript first presents a concise overview of the model previously discussed, followed by the discussion on the role of respective mechanism(s) in origins and development of metazoa. Finally, a reflection on the concept in relation to the prominent evolutionary models is put forward to illustrate a broader context of what is being discussed.

中文翻译:

生存决定论的活力:微妙的进化论渐进主义与强健的系统发育飞跃交织。

根据已报道的许多疾病的发现,关于生存确定性概念的讨论先前集中于其在早期单细胞生物进化中的主要作用。认为这种平行的基本原理是,多细胞生物可被视为半自治的单细胞实体的复杂菌落,因此,各种疾病被描述为在环境中激活各自生存机制所引起的状况。如此强大的压力响应。在这些情况下讨论的细胞机制在其他生物学过程中起着多种作用。考虑到后生动物在其进化中已经传播了很长时间,因此可以将所提出的概念进一步扩展到讨论在后生动物的发育中实施相应生存途径的机制。该手稿首先简要概述了先前讨论的模型,然后讨论了相应机制在后生动物起源和发展中的作用。最后,对与重要的进化模型相关的概念进行了反思,以说明所讨论内容的更广泛的上下文。随后讨论了相应机制在后生动物起源和发展中的作用。最后,对与重要的进化模型相关的概念进行了反思,以说明所讨论内容的更广泛的上下文。随后讨论了相应机制在后生动物起源和发展中的作用。最后,对与重要的进化模型相关的概念进行了反思,以说明所讨论内容的更广泛的上下文。
更新日期:2017-06-19
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