This study demonstrates the potential applicability of the UV mutant Yarrowia lipolytica MK1 for the valorisation of glycerol and erythritol production in a chemostat culture. The aim of this research is to investigate the optimal C:N ratio in the feeding medium in order to enhance erythritol production. The highest erythritol concentration, at 113.1 g/L with a volumetric erythritol production rate of 1.1 g/(L·h) and a yield of 0.57 g/g, was obtained in the feeding medium with a C:N ratio of 80:1. Moreover, no residual glycerol was observed in the culture broth during cultivation. The chemical composition of the biomass was analysed. The contents of lysine and threonine in the biomass protein amino acid profile were higher than those required by the FAO/WHO for fodder yeast.

中文翻译：

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解脂耶氏酵母MK1从甘油连续生产赤藓糖醇的有效方法。

这项研究证明了紫外线突变体解脂耶氏酵母MK1在化学恒温器培养物中甘油和赤藓糖醇生产的增值潜力。这项研究的目的是研究进料培养基中的最佳C：N比，以提高赤藓糖醇的产量。在进料介质中，C：N比为80：1时，最高赤藓糖醇浓度为113.1 g / L，体积赤藓糖醇生产率为1.1 g /（L·h），产量为0.57 g / g。 。此外，在培养期间在培养液中没有观察到残留的甘油。分析了生物质的化学组成。生物量蛋白质氨基酸谱中赖氨酸和苏氨酸的含量高于粮农组织/世界卫生组织对饲料酵母的要求。