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Methods of Isolation and Characterization of Stem Cells from Different Regions of Oral Cavity Using Markers: A Systematic Review.
International Journal of Stem Cells ( IF 2.3 ) Pub Date : 2017-5-24 , DOI: 10.15283/ijsc17010
Kavarthapu Avinash 1 , Sankari Malaippan 1 , Jayakumar Nadathur Dooraiswamy 1
Affiliation  

Periodontitis is a destructive inflammatory disorder of the periodontium caused by the destruction of periodontal tissues namely the PDL, cementum, alveolar bone, and gingiva. Once these tissues are lost, the foremost goal of periodontal therapy is to regenerate the diseased tissues if possible to their original form, architecture, and function. Various regenerative procedures were employed and still a gap was found in achieving the goal. As stem cells are characterized by their ability to self-renew and differentiate to produce specialized cells, there could be a possibility of using them for regenerative therapy. Recently, dental tissues such as the PDL, the dental pulp and the tooth follicle have been recognized as readily available sources of adult stem cells.

中文翻译:

使用标记分离和表征口腔不同区域干细胞的方法:系统综述。

牙周炎是由牙周组织PDL,牙骨质,牙槽骨和牙龈破坏引起的牙周炎性破坏性疾病。一旦这些组织丢失,牙周治疗的首要目标就是尽可能使患病的组织再生为其原始形态,结构和功能。采用了各种再生程序,但在实现目标方面仍然存在差距。由于干细胞的特征在于其自我更新和分化以产生专门细胞的能力,因此可能将其用于再生治疗。近来,诸如PDL,牙髓和牙囊的牙齿组织已被认为是成年干细胞的容易获得的来源。
更新日期:2020-08-21
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