Objectives: To evaluate the association between nutritional status, resting energy expenditure (REE), and protein oxidative stress in patients after kidney transplantation (KT).

Methodology: The study evaluated 35 patients transplanted at the time of hospital discharge and 3 months after regarding: body composition, REE (by indirect calorimetry), and injury factor (IF); serum urea, creatinine, glucose, albumin, total protein, advanced oxidation protein products (AOPP), vitamin C.

Results: Three months after discharge, there was an improvement in renal function, nutritional status, and oxidative stress, with a standardization in the REE/kg. There was an increase in body weight, mainly in fat mass. The correlations showed that a greater cold ischemia time resulted in a deeper decline in vitamin C; a longer hospital length stay resulted in a greater reduction in AOPP; the higher preoperative body weight showed greater increases in body fat and glucose after transplantation. For decreases in REE and IF, there were increases in total protein. Finally, at hospital discharge there was a greater gain in weight, lower albumin, and total protein among individuals who had rejection episodes.

Discussion: The KT improves many of metabolic abnormalities, with the improvement of nutritional status, oxidative stress, and normalization of REE.

目的：评估肾移植 (KT) 后患者的营养状况、静息能量消耗 (REE) 和蛋白质氧化应激之间的关系。

方法：该研究评估了 35 名在出院时和 3 个月后移植的患者：身体成分、REE（通过间接量热法）和损伤因子（IF）；血清尿素、肌酐、葡萄糖、白蛋白、总蛋白、高级氧化蛋白产物 (AOPP)、维生素 C。

结果：出院三个月后，肾功能、营养状况和氧化应激均有改善，REE/kg 标准化。体重增加，主要是脂肪量。相关性表明，冷缺血时间越长，维生素 C 的下降越深；住院时间越长，AOPP 下降幅度越大；较高的术前体重表明移植后体脂和葡萄糖增加较多。对于 REE 和 IF 的减少，总蛋白质增加。最后，在出院时，有排斥反应的个体体重增加更多，白蛋白和总蛋白降低。

讨论： KT 改善了许多代谢异常，改善了营养状况、氧化应激和 REE 的正常化。