Neuroinflammation is involved in the pathogenesis of neurodegenerative disorders. Conditioned medium (CM) derived from bone marrow mesenchymal stem cells (MSCs) revealed substantial benefits due to its rich content of trophic factors. Salidroside (Sal), extracted from Rhodiola rosea, is known for its anti-inflammatory and neuroprotective effects. This study was designed to investigate the effect of Sal pretreated CM (CM-Sal) derived from bone marrow MSCs in lipopolysaccharide (LPS) induced neuroinflammation.

中文翻译：

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源自红景天苷预处理的间充质干细胞培养物的条件培养基可改善小鼠脂多糖诱导的脑神经炎症 - 组织学和免疫组织化学研究。

神经炎症与神经退行性疾病的发病机制有关。源自骨髓间充质干细胞 (MSCs) 的条件培养基 (CM) 由于其丰富的营养因子含量而显示出巨大的益处。从红景天中提取的红景天苷 (Sal) 以其抗炎和神经保护作用而闻名。本研究旨在研究来源于骨髓间充质干细胞的经 Sal 预处理的 CM (CM-Sal) 在脂多糖 (LPS) 诱导的神经炎症中的作用。