Efficacy of Human Platelet Rich Fibrin Exudate vs Fetal Bovine Serum on Proliferation and Differentiation of Dental Pulp Stem Cells.,International Journal of Stem Cells

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Efficacy of Human Platelet Rich Fibrin Exudate vs Fetal Bovine Serum on Proliferation and Differentiation of Dental Pulp Stem Cells.
International Journal of Stem Cells ( IF 2.5 ) Pub Date : 2017-2-22 , DOI: 10.15283/ijsc16067
Mahmoud A Saeed ₁ , Mohamed Abd El-Rahman ₂ , Mohamed E Helal ₂ , Ahmed R Zaher ₂ , Mohammed E Grawish _{1,

2}

Affiliation

The imperative role of dental pulp stem cells (DPSCs) in regenerative therapy demands an in-vitro expansion which must deal with the safety and ethical problems associated with fetal bovine serum (FBS). The primary aim of this study was to compare the effects of human platelet rich fibrin (hPRF) exudate V_s FBS on proliferation and osteodifferentiation of human dental pulp stem cells (hDPSCs). The secondary one was to determine the optimum concentration of hPRF exudate inducing hDPSCs proliferation and osteodifferentiation.

中文翻译：

人血小板富含纤维蛋白渗出液与胎牛血清对牙髓干细胞增殖和分化的影响。

牙髓干细胞 (DPSC) 在再生治疗中的重要作用要求体外扩增必须处理与胎牛血清 (FBS) 相关的安全和伦理问题。本研究的主要目的是比较人富含血小板的纤维蛋白 (hPRF) 渗出物V _s FBS 对人牙髓干细胞 (hDPSCs) 增殖和骨分化的影响。第二个是确定hPRF渗出液诱导hDPSCs增殖和骨分化的最佳浓度。

更新日期：2020-08-21

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