The treatment of clay minerals with a preliminary acid wash and titration to pH 7 has proven to generate catalysts for the most interesting of oligomerization reactions in which activated RNA-nucleotides generate oligomers up to 40-mers. Significantly, not all clay minerals become catalytic following this treatment and none are catalytic in the absence of such treatment. The washing procedure has been modified and explored further using phosphoric acid and the outcomes are compared to those obtained when clay samples are prepared following a hydrochloric acid wash.

中文翻译：

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RNA 合成用蒙脱土催化剂制备中盐酸和磷酸处理的比较。


通过初步酸洗和滴定至 pH 7 来处理粘土矿物已被证明可以产生最有趣的低聚反应的催化剂，其中活化的 RNA 核苷酸产生高达 40 聚体的低聚物。值得注意的是，并非所有粘土矿物在经过这种处理后都具有催化作用，并且在没有这种处理的情况下，没有一种粘土矿物具有催化作用。使用磷酸对洗涤程序进行了修改和进一步探索，并将结果与​​在盐酸洗涤后制备粘土样品时获得的结果进行了比较。