There has only been limited research into the predictors of readmission in bipolar disorder. We carried out a 1-year follow-up of patients discharged from a single mental health unit following admission for treatment of an acute bipolar episode. Of 519 patients followed up for 1 year, 167 (32.2%) were readmitted. There was no association between readmission and any drug regimen. Prescription of antidepressants at discharge was not associated with increased risk of readmission [odds ratio (OR): 0.99, 95% confidence interval (CI): 0.98-1.01]. Among demographic factors, only smoking (OR: 1.75, 95% CI: 1.14-2.75) and age range of 42-53 years (OR: 1.99, 95% CI: 1.15-3.43) conferred an increased risk of readmission. Individually optimized drug treatment regimens are equally effective in practice. It is not clear why smoking is associated with readmission.

中文翻译：

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双相情感障碍患者的自然队列中再次住院的预测因素。

对于双相情感障碍再入的预测因素，只有有限的研究。我们对入院后因急性双相发作而从单个精神卫生部门出院的患者进行了为期1年的随访。在519位接受了1年随访的患者中，有167位（32.2％）重新入院。再入院与任何药物治疗之间均无关联。出院时开具抗抑郁药处方与再入院风险增加无关[比值比（OR）：0.99，95％置信区间（CI）：0.98-1.01]。在人口统计学因素中，仅吸烟（OR：1.75，95％CI：1.14-2.75）和年龄范围为42-53岁（OR：1.99，95％CI：1.15-3.43）会增加再次入院的风险。个体优化的药物治疗方案在实践中同样有效。