People living in regions of low socioeconomic status are thought to be prone to higher exposures to environmental pollutants, poor nutrition, and numerous preventable diseases and infections. Poverty correlates with pollution and malnutrition; however, limited studies examined their interrelationship. The well-studied, deleterious health effects attributed to environmental pollutants and poor nutrition may act in combination with produce more severe adverse health outcomes than any one factor alone. Deficiencies in specific nutrients render the body more susceptible to injury which may influence the pathways that serve as the mechanistic responses to ambient air pollutants. This review (1) explores specific micronutrients that are of global concern, (2) explains how these nutrients may impact the body's response to ambient air pollution, and (3) provides guidance on designing animal models of nutritional deficiency. It is likely that those individuals who reside in regions of high ambient air pollution are similarly malnourished. Therefore, it is important that research identifies specific nutrients of concern and their impact in identified regions of high ambient air pollution.

中文翻译：

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微量营养素在对环境空气污染物的响应中的作用：研究设计的潜在机制和建议。

人们认为，生活在社会经济地位低下的地区的人们更容易受到环境污染物，营养不良以及许多可预防的疾病和感染的影响。贫穷与污染和营养不良有关；但是，有限的研究检查了它们之间的相互关系。与环境因素和营养不良有关的经过充分研究的有害健康影响可能与单独产生任何一种因素相比，会产生更严重的不利健康后果。特定营养素的缺乏使人体更容易受到伤害，这可能会影响对环境空气污染物产生机械反应的途径。这篇评论（1）探索了全球关注的特定微量营养素，（2）解释了这些营养素如何影响人体对周围空气污染的反应，（3）为设计营养缺乏的动物模型提供指导。那些居住在空气污染高的地区的人可能营养不良。因此，重要的是，研究必须确定所关注的特定营养素及其在确定的高环境空气污染区域中的影响。