Disorders in spatial exploration can be expressed in a disorganized fashion of target cancellation. There is debate regarding whether disorganized search is related to stroke in general, to right brain damage or to unilateral spatial neglect (USN) in particular. In this study, 280 stroke patients and 37 healthy control subjects performed a computerized shape cancellation test. We investigated the number of perseverations and several outcome measures regarding disorganized search: Consistency of search direction (best r), distance between consecutive cancelled targets and intersections with paths between previous cancelled targets. We compared performance between patients with left and right brain damage (L, R) and with and without USN (USN+, USN−), resulting in four subgroups: LUSN−, RUSN−, LUSN+, and RUSN+. Higher numbers of intersections were found for the left brain‐ and right brain‐damaged patients with USN and for the right brain‐damaged patients without USN, compared to healthy control subjects. Furthermore, right brain‐damaged patients with USN showed a higher number of intersections compared to right brain‐damaged patients without USN and compared to left brain‐damaged patients with USN. To conclude, disorganized search was most strongly related to the neglect syndrome, and patients with more severe USN were even more impaired.

中文翻译：

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在知道自己去过哪里之前，您永远不会知道自己要去的地方：中风后的混乱搜索。

空间探索中的障碍可以以目标取消的杂乱无章的方式表达。关于杂乱无章的搜索是一般性地与中风有关，还是与右脑损伤或特别是与单侧空间疏忽（USN）有关，存在争议。在这项研究中，280名中风患者和37名健康对照受试者进行了计算机形状消除测试。我们调查了关于无序搜索的持之以恒的数量和几种结果度量：搜索方向的一致性（最佳r），连续被取消目标之间的距离以及交叉点以及先前已取消目标之间的路径。我们比较了左，右脑损伤（左，右）和有或没有USN（USN +，USN-）的患者之间的表现，结果分为四个亚组：LUSN-，RUSN-，LUSN +和RUSN +。与健康对照组相比，发现有USN的左脑和右脑受损患者以及没有USN的右脑受损患者的交叉点数量更高。此外，与没有USN的右脑受损患者以及与USN的左脑受损患者相比，USN的右脑受损患者显示出更多的交集。总而言之，无序搜索与疏忽综合症最密切相关，USN较重的患者受损更大。