This study continues a longitudinal analysis of rhesus macaque social behavior following bilateral neonatal ibotenic acid lesions of the amygdala or hippocampus, or sham operations. The social behavior of female subjects was evaluated at a critical developmental time point-the transition to adulthood. At approximately 4 years of age, female subjects were housed in small groups with other female subjects and reproductively viable adult males. As compared with neurologically intact control animals and animals with early amygdala damage, animals with early hippocampal damage were more social with their female peers. In contrast, as compared with control animals, animals with early amygdala damage spent less time with the males, engaged less frequently in behaviors typical of reproductive consortships, had higher frequencies of self-directed stereotypies, and became pregnant later. Males also generated fewer communicative signals toward animals with early amygdala damage than to control animals and animals with early hippocampus damage. Rates of sexual behavior were generally low for all animals, and there were no lesion-based differences in their frequencies. Discriminant function analyses demonstrated that patterns of affiliative social behaviors differed across the 3 experimental groups, both in terms of the social behaviors directed to the males, and the social behaviors generated by the males toward the females. In 4 of the 5 social groups, amygdala-lesioned animals were lowest ranked, potentially contributing to reduced sociability interactions with males. Other potential mechanisms and the experiments needed to elucidate them are discussed. (PsycINFO Database Record

中文翻译：

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早期杏仁核或海马体损伤会影响青少年女性在群体形成过程中的社会行为。

本研究继续对新生儿双侧杏仁核或海马或假手术后的猕猴社会行为进行纵向分析。女性受试者的社会行为在关键的发育时间点（向成年期过渡）进行评估。大约 4 岁时，女性受试者与其他女性受试者和具有生育能力的成年男性一起被安置在小组中。与神经系统完整的对照动物和早期杏仁核损伤的动物相比，早期海马损伤的动物与雌性同伴的社交能力更强。相比之下，与对照动物相比，早期杏仁核受损的动物与雄性相处的时间更少，参与典型生殖配偶行为的频率也更低，自我导向刻板印象的频率更高，并且怀孕较晚。与对照动物和早期海马体损伤的动物相比，雄性对早期杏仁核损伤的动物产生的交流信号也较少。所有动物的性行为率普遍较低，并且其频率不存在基于病变的差异。判别函数分析表明，3 个实验组的亲和社会行为模式不同，无论是针对男性的社会行为，还是男性对女性产生的社会行为。在 5 个社会群体中的 4 个群体中，杏仁核受损的动物排名最低，这可能导致与雄性的社交互动减少。讨论了其他潜在的机制以及阐明它们所需的实验。（PsycINFO 数据库记录