The present study was aimed to investigate behavioural and biochemical effects of chronic exposure of amplitude modulated and non-modulated microwave radiation on laboratory mice. Chronic microwave exposures were executed with 2.45 GHz of either modulated (power density, 0.029 mW/cm²; specific absorption rate, 0.019 W/Kg with sinusoidal modulation of 400 Hz) or nonmodulated continuous sinusoidal wave (power density, 0.033 mW/cm²; specific absorption rate, 0.023 W/Kg) for 2 hrs daily for 1 month. Mice subjected to non-modulated microwave exposure had significantly increased acetylcholinesterase activity and increased intracellular calcium and nitric oxide levels in the cerebral cortex and hippocampus, and also had increased glucose and corticosterone levels in blood compared to control mice. These non-modulated microwave-exposed mice exhibited anxiety-like and depression-like behaviours. In contrast, mice exposed to modulated microwave for the same period did not show such changes in concomitant biochemical and behavioural analyses. These results suggest that chronic non-modulated microwave, but not modulated microwave, radiation may cause anxiety-like and depression-like behaviours and calcium- and NO-related biochemical changes in the brain.

中文翻译：

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小鼠的慢性非调制微波辐射在大脑中产生焦虑样和抑郁样行为以及钙和NO相关的生化变化。

本研究旨在调查在实验小鼠上长期暴露的调幅和非调制微波辐射的行为和生化效应。使用2.45 GHz调制（功率密度为0.029 mW / cm ²；比吸收率为0.019 W / Kg，正弦调制为400 Hz）或未经调制的连续正弦波（功率密度为0.033 mW / cm ²）进行2.45 GHz慢性微波照射; 比吸收率（0.023 W / Kg），每天2小时，持续1个月。与对照小鼠相比，接受非调制微波照射的小鼠的大脑皮层和海马区的乙酰胆碱酯酶活性显着提高，细胞内钙和一氧化氮水平升高，血液中的葡萄糖和皮质酮水平也升高。这些未调制的微波暴露小鼠表现出焦虑样和抑郁样行为。相反，在同一时期暴露于调制微波的小鼠在伴随的生化和行为分析中未显示出这种变化。这些结果表明，慢性非调制微波（而不是调制微波）辐射可能会导致大脑出现焦虑样和抑郁样行为以及钙和NO相关的生化变化。