With the global demand for dairy protein for consumption growing annually, there has been increasing activity in the research field of dairy protein synthesis and production. From a manipulation perspective, it is more difficult to use live cattle for laboratory studies on the production of milk as well as of dairy protein such as casein, as compared with using laboratory animals like rodents. Therefore, we aimed to develop a mouse model of bovine mammary alveolar ducts for laboratory-scale studies. We studied the formation of the bovine mammary gland ductal structure by transplanting the MAC-T bovine alveolar cell line into mice.

中文翻译：

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通过移植与基质胶混合的牛乳腺上皮细胞在免疫缺陷小鼠中再生牛乳腺。

随着全球对乳蛋白消费需求的逐年增长，乳蛋白合成和生产的研究领域也越来越活跃。从操作的角度来看，与使用啮齿动物等实验室动物相比，使用活牛进行牛奶生产以及酪蛋白等乳蛋白生产的实验室研究更加困难。因此，我们的目标是开发一种用于实验室规模研究的牛乳腺肺泡管小鼠模型。我们通过将 MAC-T 牛肺泡细胞系移植到小鼠体内来研究牛乳腺导管结构的形成。