Schwann-like (SC-like) cells induced from adipose-derived stem cells (ASCs) may be one of the ideal alternative cell sources for obtaining Schwann cells (SCs). They can be used for treating peripheral nerve injuries. Co-culture with SCs or exposure to glial growth factors are commonly used for differentiation of ASCs to SC-like cells. However, the effect of initial cell density as an inductive factor on the differentiation potential of ASCs into the SC-like cells has not been yet investigated.

中文翻译：

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细胞密度对大鼠脂肪干细胞向雪旺细胞样细胞分化效率的影响。

从脂肪干细胞 (ASCs) 诱导的雪旺细胞样 (SC-like) 细胞可能是获得雪旺细胞 (SCs) 的理想替代细胞来源之一。它们可用于治疗周围神经损伤。与 SC 共培养或暴露于神经胶质生长因子通常用于将 ASC 分化为 SC 样细胞。然而，尚未研究初始细胞密度作为诱导因子对 ASC 向 SC 样细胞分化潜能的影响。