The "doctor in the loop" is a new paradigm in information-driven medicine, picturing the doctor as authority inside a loop supplying an expert system with information on actual patients, treatment results, and possible additional (side-)effects, including general information in order to enhance data-driven medical science, as well as giving back treatment advice to the doctor himself. While this approach can be very beneficial for new medical approaches like P4 medicine (personal, predictive, preventive, and participatory), it also relies heavily on the authenticity of the data and thus increases the need for secure and reliable databases. In this paper, we propose a solution in order to protect the doctor in the loop against responsibility derived from manipulated data, thus enabling this new paradigm to gain acceptance in the medical community. This work is an extension of the conference paper Kieseberg et al. (Brain Informatics and Health, 2015), which includes extensions to the original concept.

中文翻译：

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环路中医生的防篡改审核和控制系统。

“回路医生”是信息驱动医学的新范例，将医生形象化为回路内的权威，为专家系统提供有关实际患者，治疗结果以及可能的附加（副作用）信息的信息，包括一般信息为了加强数据驱动的医学科学，并向医生本人提供治疗建议。尽管这种方法对于P4医学这样的新医学方法（个人，预测性，预防性和参与性）可能非常有益，但它也严重依赖于数据的真实性，因此增加了对安全可靠的数据库的需求。在本文中，我们提出了一种解决方案，以保护循环中的医生免受来自操纵数据的责任，从而使这种新范例在医学界获得认可。这项工作是会议论文Kieseberg等人的扩展。（Brain Informatics and Health，2015），其中包括对原始概念的扩展。