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Frontal lobe regulation of blood glucose levels: support for the limited capacity model in hostile violence-prone men.
Brain Informatics Pub Date : 2016-02-01 , DOI: 10.1007/s40708-016-0034-6
Robert P Walters 1 , Patti Kelly Harrison 1 , Ransom W Campbell 1 , David W Harrison 1
Affiliation  

Hostile men have reliably displayed an exaggerated sympathetic stress response across multiple experimental settings, with cardiovascular reactivity for blood pressure and heart rate concurrent with lateralized right frontal lobe stress (Trajanoski et al., in Diabetes Care 19(12):1412-1415, 1996; see Heilman et al., in J Neurol Neurosurg Psychiatry 38(1):69-72, 1975). The current experiment examined frontal lobe regulatory control of glucose in high and low hostile men with concurrent left frontal lobe (Control Oral Word Association Test [verbal]) or right frontal lobe (Ruff Figural Fluency Test [nonverbal]) stress. A significant interaction was found for Group × Condition, F (1,22) = 4.16, p ≤ .05 with glucose levels (mg/dl) of high hostile men significantly elevated as a function of the right frontal stressor (M = 101.37, SD = 13.75) when compared to the verbal stressor (M = 95.79, SD = 11.20). Glucose levels in the low hostile group remained stable for both types of stress. High hostile men made significantly more errors on the right frontal but not the left frontal stressor (M = 17.18, SD = 19.88) when compared to the low hostile men (M = 5.81, SD = 4.33). These findings support our existing frontal capacity model of hostility (Iribarren et al., in J Am Med Assoc 17(19):2546-2551, 2000; McCrimmon et al., in Physiol Behav 67(1):35-39, 1999; Brunner et al., in Diabetes Care 21(4):585-590, 1998), extending the role of the right frontal lobe to regulatory control over glucose mobilization.

中文翻译:


血糖水平的额叶调节:支持敌对暴力倾向男性的有限能力模型。



敌对男性在多个实验环境中可靠地表现出夸大的交感神经应激反应,心血管对血压和心率的反应性与偏侧右额叶应激同时发生(Trajanoski 等人,in Diabetes Care 19(12):1412-1415, 1996 ;参见 Heilman 等人,J Neurol Neurosurg Psychiatry 38(1):69-72, 1975)。当前的实验检查了高和低敌意男性的额叶对葡萄糖的调节控制,同时左额叶(控制口语联想测试[口头])或右额叶(拉夫图形流畅性测试[非语言])压力。发现组 × 条件存在显着的相互作用,F (1,22) = 4.16,p ≤ .05 与高敌意男性的葡萄糖水平 (mg/dl) 显着升高,作为右额叶应激源的函数 (M = 101.37, SD = 13.75)与言语压力源(M = 95.79,SD = 11.20)相比。对于两种类型的应激,低敌意组的血糖水平保持稳定。与低敌意男性(M = 5.81,SD = 4.33)相比,高敌意男性在右额叶压力源上犯的错误明显更多,但在左额叶压力源上则不然(M = 17.18,SD = 19.88)。这些发现支持我们现有的敌意额叶能力模型(Iribarren 等人,in J Am Med Assoc 17(19):2546-2551, 2000;McCrimmon 等人,in Physiol Behav 67(1):35-39, 1999 ;Brunner 等人,在 Diabetes Care 21(4):585-590, 1998)中,将右额叶的作用扩展到对葡萄糖动员的调节控制。
更新日期:2019-11-01
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