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Frontal lobe regulation of blood glucose levels: support for the limited capacity model in hostile violence-prone men.
Brain Informatics Pub Date : 2016-10-18 , DOI: 10.1007/s40708-016-0034-6
Robert P Walters 1 , Patti Kelly Harrison 1 , Ransom W Campbell 1 , David W Harrison 1
Affiliation  

Hostile men have reliably displayed an exaggerated sympathetic stress response across multiple experimental settings, with cardiovascular reactivity for blood pressure and heart rate concurrent with lateralized right frontal lobe stress (Trajanoski et al., in Diabetes Care 19(12):1412-1415, 1996; see Heilman et al., in J Neurol Neurosurg Psychiatry 38(1):69-72, 1975). The current experiment examined frontal lobe regulatory control of glucose in high and low hostile men with concurrent left frontal lobe (Control Oral Word Association Test [verbal]) or right frontal lobe (Ruff Figural Fluency Test [nonverbal]) stress. A significant interaction was found for Group × Condition, F (1,22) = 4.16, p ≤ .05 with glucose levels (mg/dl) of high hostile men significantly elevated as a function of the right frontal stressor (M = 101.37, SD = 13.75) when compared to the verbal stressor (M = 95.79, SD = 11.20). Glucose levels in the low hostile group remained stable for both types of stress. High hostile men made significantly more errors on the right frontal but not the left frontal stressor (M = 17.18, SD = 19.88) when compared to the low hostile men (M = 5.81, SD = 4.33). These findings support our existing frontal capacity model of hostility (Iribarren et al., in J Am Med Assoc 17(19):2546-2551, 2000; McCrimmon et al., in Physiol Behav 67(1):35-39, 1999; Brunner et al., in Diabetes Care 21(4):585-590, 1998), extending the role of the right frontal lobe to regulatory control over glucose mobilization.

中文翻译:

额叶对血糖水平的调节:支持易受暴力侵害的男性的能力有限模型。

敌对的男性已经可靠地显示出在多种实验情况下的过度的交感应激反应,心血管反应的血压和心率与右额叶偏侧应激同时发生(Trajanoski等,in Diabetes Care 19(12):1412-1415,1996 ;参见Heilman等人,在J Neurol Neurosurg Psychiatry 38(1):69-72,1975)。当前的实验研究了高和低敌对男性并发左额叶(控制口语单词联想测试[语言])或右额叶(Ruff形象流利度测试[非语言])应激时额叶对葡萄糖的调节控制。研究发现,组×条件,F(1,22)= 4.16,p≤.05与高度敌对男性的葡萄糖水平(mg / dl)呈显着的交互作用,而该水平随右额侧应激源的升高而显着升高(M = 101.37, SD = 13。75)与言语压力源相比(M = 95.79,SD = 11.20)。在低压力组中,两种压力下的葡萄糖水平均保持稳定。与低敌对男性(M = 5.81,SD = 4.33)相比,高敌对男性在右额肌上的错误明显多于左额肌(M = 17.18,SD = 19.88)。这些发现支持了我们现有的敌对行动前沿能力模型(Iribarren等,J Am Med Assoc 17(19):2546-2551,2000; McCrimmon等,Physiol Behav 67(1):35-39,1999) ; Brunner等人,在Diabetes Care 21(4):585-590,1998)中,将右额叶的作用扩展到葡萄糖动员的调节控制上。与低敌对男性(M = 5.81,SD = 4.33)相比,高敌对男性在右额肌上的错误明显多于左额肌(M = 17.18,SD = 19.88)。这些发现支持了我们现有的敌对行动前沿能力模型(Iribarren等,J Am Med Assoc 17(19):2546-2551,2000; McCrimmon等,Physiol Behav 67(1):35-39,1999) ; Brunner等人,在Diabetes Care 21(4):585-590,1998)中,将右额叶的作用扩展到葡萄糖动员的调节控制上。与低敌对男性(M = 5.81,SD = 4.33)相比,高敌对男性在右额肌上的错误明显多于左额肌(M = 17.18,SD = 19.88)。这些发现支持了我们现有的敌对行动前沿能力模型(Iribarren等,J Am Med Assoc 17(19):2546-2551,2000; McCrimmon等,Physiol Behav 67(1):35-39,1999) ; Brunner等人,在Diabetes Care 21(4):585-590,1998)中,将右额叶的作用扩展到葡萄糖动员的调节控制上。
更新日期:2019-11-01
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