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Toward the holistic, reference, and extendable atlas of the human brain, head, and neck.
Brain Informatics Pub Date : 2015-06-01 , DOI: 10.1007/s40708-015-0012-4
Wieslaw L Nowinski 1
Affiliation  

Despite numerous efforts, a fairly complete (holistic) anatomical model of the whole, normal, adult human brain, which is required as the reference in brain studies and clinical applications, has not yet been constructed. Our ultimate objective is to build this kind of atlas from advanced in vivo imaging. This work presents the taxonomy of our currently developed brain atlases and addresses the design, content, functionality, and current results in the holistic atlas development as well as atlas usefulness and future directions. We have developed to date 35 commercial brain atlases (along with numerous research prototypes), licensed to 63 companies and institutions, and made available to medical societies, organizations, medical schools, and individuals. These atlases have been applied in education, research, and clinical applications. Hundreds of thousands of patients have been treated by using our atlases. Based on this experience, the first version of the holistic and reference atlas of the brain, head, and neck has been developed and made available. The atlas has been created from multispectral 3 and 7 Tesla and high-resolution CT in vivo scans. It is fully 3D, scalable, interactive, and highly detailed with about 3,000 labeled components. This atlas forms a foundation for the development of a multi-level molecular, cellular, anatomical, physiological, and behavioral brain atlas platform.

中文翻译:

走向人脑,头部和颈部的整体,参考和可扩展图集。

尽管付出了许多努力,但尚未构建出完整的,完整的,完整的,成年的人脑的解剖模型,这在脑研究和临床应用中需要作为参考。我们的最终目标是从先进的体内成像中构建出这种图集。这项工作介绍了我们目前开发的脑图谱的分类法,并论述了整体图谱开发的设计,内容,功能和当前结果以及图谱的实用性和未来方向。迄今为止,我们已经开发了35幅商业大脑地图集(以及许多研究原型),已授权63家公司和机构使用,并提供给医学社团,组织,医学院校和个人。这些地图集已应用于教育,研究和临床应用。使用我们的地图集已治疗了成千上万的患者。基于此经验,已经开发并提供了大脑,头部和颈部的整体图谱和参考图谱的第一个版本。该图集由多光谱3和7特斯拉以及高分辨率CT体内扫描创建而成。它是完全3D的,可伸缩的,交互式的,并且高度详细,带有大约3,000个带有标签的组件。该图集为开发多层次的分子,细胞,解剖,生理和行为性脑图集平台奠定了基础。该图集是根据多光谱3和7特斯拉以及高分辨率CT体内扫描创建的。它是完全3D的,可伸缩的,交互式的,并且高度详细,带有大约3,000个带有标签的组件。该图集为开发多层次的分子,细胞,解剖,生理和行为性脑图集平台奠定了基础。该图集由多光谱3和7特斯拉以及高分辨率CT体内扫描创建而成。它是完全3D的,可伸缩的,交互式的,并且高度详细,带有大约3,000个带有标签的组件。该图集为开发多层次的分子,细胞,解剖,生理和行为性脑图集平台奠定了基础。
更新日期:2019-11-01
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