Moonlighting proteins are multifunctional proteins that participate in unrelated biological processes and that are not the result of gene fusion. A certain number of these proteins have been characterized in yeasts, and the easy genetic manipulation of these microorganisms has been useful for a thorough analysis of some cases of moonlighting. As the awareness of the moonlighting phenomenon has increased, a growing number of these proteins are being uncovered. In this review, we present a crop of newly identified moonlighting proteins from yeasts and discuss the experimental evidence that qualifies them to be classified as such. The variety of moonlighting functions encompassed by the proteins considered extends from control of transcription to DNA repair or binding to plasminogen. We also discuss several questions pertaining to the moonlighting condition in general. The cases presented show that yeasts are important organisms to be used as tools to understand different aspects of moonlighting proteins.

中文翻译：

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酵母中月光照蛋白的扩展图景。

月色蛋白是多功能蛋白，它们参与无关的生物过程，而不是基因融合的结果。酵母中已鉴定出一定数量的这些蛋白质，对这些微生物进行简单的遗传操作对于彻底分析某些月光照情况很有用。随着对月光现象的认识的提高，越来越多的这些蛋白质被发现。在这篇综述中，我们提出了一种新近发现的来自酵母的月光照蛋白，并讨论了将其归类为合格的实验证据。所考虑的蛋白质所包含的各种月光功能，从转录控制到DNA修复或与纤溶酶原的结合，应有尽有。我们还将讨论与月光照明条件有关的几个问题。提出的案例表明，酵母菌是重要的生物，可以用作了解月光蛋白不同方面的工具。