The National Asthma Education and Prevention Program's Expert Panel Report 3, Guidelines for the Diagnosis and Management of Asthma does not recommend antibiotics for the management of acute episodes of asthma exacerbation. Macrolides seem to have some potential effect beyond or in addition to their antibacterial effect. It has been reported that macrolides may potentially benefit patients with chronic inflammatory airway diseases due to their antibacterial, antiviral, and/or anti-inflammatory effects. This review presents recent data on use of azithromycin in prevention and management of acute exacerbation of respiratory symptoms in infants and young children.

中文翻译：

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学龄前儿童急性喘息发作大环内酯类药物。

国家哮喘教育和预防计划专家小组报告3，《哮喘诊断和治疗指南》不建议使用抗生素来治疗哮喘急性发作。大环内酯类药物除具有抗菌作用外，还具有某些潜在作用。据报道，大环内酯类药物由于其抗菌，抗病毒和/或抗炎作用，可能潜在地使患有慢性炎症性气道疾病的患者受益。这篇综述提供了关于使用阿奇霉素预防和管理婴幼儿呼吸道症状急性加重的最新数据。