Recent progress in retinal image acquisition techniques, including optical coherence tomography (OCT) and scanning laser ophthalmoscopy (SLO), combined with improved performance of adaptive optics (AO) instrumentation, has resulted in improvement in the quality of in vivo images of cellular structures in the human retina. Here, we present a short review of progress on developing AO-OCT instruments. Despite significant progress in imaging speed and resolution, eye movements present during acquisition of a retinal image with OCT introduce motion artifacts into the image, complicating analysis and registration. This effect is especially pronounced in high-resolution datasets acquired with AO-OCT instruments. Several retinal tracking systems have been introduced to correct retinal motion during data acquisition. We present a method for correcting motion artifacts in AO-OCT volume data after acquisition using simultaneously captured adaptive optics-scanning laser ophthalmoscope (AO-SLO) images. We extract transverse eye motion data from the AO-SLO images, assign a motion adjustment vector to each AO-OCT A-scan, and re-sample from the scattered data back onto a regular grid. The corrected volume data improve the accuracy of quantitative analyses of microscopic structures.

中文翻译：

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开发用于体内视网膜成像的自适应光学 - 光学相干断层扫描的进展：眼动伪影的监测和校正

视网膜图像采集技术的最新进展，包括光学相干断层扫描 (OCT) 和扫描激光检眼镜 (SLO)，结合自适应光学 (AO) 仪器的改进性能，提高了细胞结构的活体图像质量。人类的视网膜。在这里，我们简要回顾了开发 AO-OCT 仪器的进展。尽管在成像速度和分辨率方面取得了重大进展，但在使用 OCT 采集视网膜图像期间出现的眼球运动会将运动伪影引入图像，使分析和配准变得复杂。这种效果在使用 AO-OCT 仪器获取的高分辨率数据集中尤为明显。已经引入了几种视网膜跟踪系统来校正数据采集过程中的视网膜运动。我们提出了一种使用同时捕获的自适应光学扫描激光检眼镜 (AO-SLO) 图像在采集后校正 AO-OCT 体积数据中的运动伪影的方法。我们从 AO-SLO 图像中提取横向眼球运动数据，为每个 AO-OCT A 扫描分配一个运动调整向量，并从分散的数据中重新采样回规则网格。校正后的体积数据提高了微观结构定量分析的准确性。