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Severe Type 2 Diabetes Induces Reversible Modifications of Endothelial Progenitor Cells Which are Ameliorate by Glycemic Control.
International Journal of Stem Cells ( IF 2.3 ) Pub Date : 2016-7-19 , DOI: 10.15283/ijsc.2016.9.1.137 Maria Rosaria De Pascale 1 , Giuseppe Bruzzese 2 , Ettore Crimi 3 , Vincenzo Grimaldi 1 , Antonio Liguori 2 , Sergio Brongo 4 , Michelangela Barbieri 5 , Antonietta Picascia 1 , Concetta Schiano 6 , Linda Sommese 1 , Nicola Ferrara 7 , Giuseppe Paolisso 5 , Claudio Napoli 1, 5, 6
International Journal of Stem Cells ( IF 2.3 ) Pub Date : 2016-7-19 , DOI: 10.15283/ijsc.2016.9.1.137 Maria Rosaria De Pascale 1 , Giuseppe Bruzzese 2 , Ettore Crimi 3 , Vincenzo Grimaldi 1 , Antonio Liguori 2 , Sergio Brongo 4 , Michelangela Barbieri 5 , Antonietta Picascia 1 , Concetta Schiano 6 , Linda Sommese 1 , Nicola Ferrara 7 , Giuseppe Paolisso 5 , Claudio Napoli 1, 5, 6
Affiliation
Circulating endothelial progenitors cells (EPCs) play a critical role in neovascularization and endothelial repair. There is a growing evidence that hyperglycemia related to Diabetes Mellitus (DM) decreases EPC number and function so promoting vascular complications.
中文翻译：
严重的2型糖尿病会诱导内皮祖细胞的可逆修饰，后者通过血糖控制得到改善。
循环内皮祖细胞（EPC）在新血管形成和内皮修复中起关键作用。越来越多的证据表明，与糖尿病（DM）相关的高血糖症会降低EPC数量和功能，从而促进血管并发症。
更新日期：2020-08-21
中文翻译：
严重的2型糖尿病会诱导内皮祖细胞的可逆修饰，后者通过血糖控制得到改善。
循环内皮祖细胞（EPC）在新血管形成和内皮修复中起关键作用。越来越多的证据表明，与糖尿病（DM）相关的高血糖症会降低EPC数量和功能，从而促进血管并发症。
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