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Therapeutic Potential of Bone Marrow-Derived Mesenchymal Stem Cells on Experimental Liver Injury Induced by Schistosoma mansoni: A Histological Study.
International Journal of Stem Cells ( IF 2.5 ) Pub Date : 2016-7-19 , DOI: 10.15283/ijsc.2016.9.1.96
Heba Fikry 1 , Sara Abdel Gawad 1 , Walaa Baher 1
Affiliation  

Bone marrow derived mesenchymal stem cells (BM-MSCs) have been proposed as effective treatment of many diseases owing to their unique ability to differentiate into other cell types in vivo. Schistosoma mansoni (S. mansoni) infection is characterized by hepatic granuloma formation around schistosome eggs at acute stage of infection, followed by hepatic fibrosis at chronic and advanced stages. Whether BM-MSCs have an ameliorative effect on hepatic tissue injury caused by S. mansoni infection or not, was inspected in the current study.

中文翻译:

曼氏血吸虫诱导的骨髓间充质干细胞对实验性肝损伤的治疗潜力:组织学研究。

骨髓来源的间充质干细胞(BM-MSC)由于其在体内分化为其他细胞类型的独特能力,已被提议作为多种疾病的有效治疗方法。曼氏血吸虫(曼氏血吸虫)感染的特征是在感染的急性阶段在血吸虫卵周围形成肝肉芽肿,然后在慢性和晚期阶段发生肝纤维化。在当前的研究中,检查了BM-MSC是否对由曼氏沙门氏菌感染引起的肝组织损伤有改善作用。
更新日期:2020-08-21
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