Type 1 Diabetes Mellitus (T1DM) is an autoimmune disorder resulting out of T cell mediated destruction of pancreatic beta cells. Immunomodulatory properties of mesenchymal stem cells may help to regenerate beta cells and/or prevent further destruction of remnant, unaffected beta cells in diabetes. We have assessed the ability of umbilical cord derived MSCs (UCMSCs) to differentiate into functional islet cells in vitro.

中文翻译：

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脐带来源的间充质干细胞可用于胰岛素生产-细胞治疗的另一种机会。

1型糖尿病（T1DM）是由T细胞介导的胰腺β细胞破坏引起的自身免疫性疾病。间充质干细胞的免疫调节特性可能有助于再生β细胞和/或防止进一步破坏残存的，未受影响的β细胞。我们评估了脐带来源的MSC（UCMSCs）在体外分化为功能性胰岛细胞的能力。