This study aims to evaluate the effect of anti-Streptococcus mutans IgY gel on quantity of S. mutans on rats' tooth surface. Sprague Dawley rats were exposed intra-orally with S. mutans Xc and were fed a caries-inducing diet 2000. The 24 rats were divided into four groups: group A had their teeth coated with IgY gel; group B received sterilized water as a control; group C had their teeth coated with IgY gel starting on the 29(th) day; and group D had their teeth coated with a gel without IgY. Plaque samples were swabbed from the anterior teeth for S. mutans colony quantification, and saliva was collected to measure immunoreactivity by enzyme-linked immunosorbent assay. The results indicated that the quantity of S. mutans in rats treated with IgY gel showed significant difference compared with the controls. After coating with IgY anti-S. mutans gel, the mean immunoreactivity in rat saliva was higher than that of the no treatment group. In conclusion, topical application with anti-S. mutans IgY gel reduced the quantity of S. mutans on the tooth surface.

中文翻译：

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局部抗变形链球菌IgY凝胶对大鼠牙齿表面变形链球菌数量的影响。

本研究旨在评估抗变形链球菌IgY凝胶对大鼠牙齿表面变形链球菌数量的影响。将Sprague Dawley大鼠口服变形链球菌Xc并喂2000年龋齿诱导饮食。24只大鼠分为四组：A组的牙齿上涂有IgY凝胶； A组的牙齿上涂有IgY凝胶； A组的牙齿上涂有IgY凝胶。B组接受无菌水作为对照；从第29天开始，C组的牙齿涂有IgY凝胶；D组的牙齿涂有不含IgY的凝胶。从前牙擦拭斑块样品以进行变形链球菌菌落定量，并收集唾液以通过酶联免疫吸附测定法测量免疫反应性。结果表明，与对照相比，用IgY凝胶处理的大鼠中变形链球菌的量显示出显着差异。用IgY抗S包被后。变形胶体后，大鼠唾液中的平均免疫反应性高于未处理组。综上所述，局部应用有抗S的作用。变形链球菌IgY凝胶可减少牙齿表面变形链球菌的数量。