Amaryllidaceae alkaloids are an example of the vast diversity of secondary metabolites with great therapeutic promise. The identification of novel compounds in this group with over 300 known structures continues to be an area of active study. The recent identification of norbelladine 4'-O-methyltransferase (N4OMT), an Amaryllidaceae alkaloid biosynthetic enzyme, and the assembly of transcriptomes for Narcissus sp. aff. pseudonarcissus and Lycoris aurea highlight the potential for discovery of Amaryllidaceae alkaloid biosynthetic genes with new technologies. Recent technical advances of interest include those in enzymology, next generation sequencing, genetic modification, nuclear magnetic resonance spectroscopy (NMR), and mass spectrometry (MS).

中文翻译：

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金莲花科生物碱：生物合成和酶发现方法。

金莲花科生物碱是次生代谢产物种类繁多的一个例子，具有广阔的治疗前景。该组中具有300多种已知结构的新型化合物的鉴定仍然是活跃的研究领域。最近鉴定出的诺贝拉定4'-O-甲基转移酶（N4OMT），金木科生物碱生物合成酶以及水仙属转录组的组装。aff。假水仙和金黄色石蒜强调了利用新技术发现石蒜科生物碱生物合成基因的潜力。最近感兴趣的技术进步包括酶学，下一代测序，基因修饰，核磁共振波谱（NMR）和质谱（MS）方面的技术进步。