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Biochemical and Parasitological Studies on the Effect of hUCB-Selected CD34(+) Progenitor/Stem Cells in Mice Infected with Schistosoma mansoni.
International Journal of Stem Cells ( IF 2.5 ) Pub Date : 2014-12-5 , DOI: 10.15283/ijsc.2014.7.2.98
Akram M Abou-Zied 1 , Rasha H Soliman 2 , Shorouk M Hefila 3 , Samir A Imam 1
Affiliation  

Placenta and blood that remained in the umbilical cord is routinely available as a discarded tissue after deliveries and it is free of any legal, moral, ethical or religious objections, providing a high number of multipotent CD34(+) progenitor and stem cells. Using ex vivo isolated CD34(+) cells from human umbilical cord blood (hUCB) have emerged as promising candidates to treat various diseases, including exogenous pathogenic infections. We have expanded to build a rational approach to study the effect of CD34(+) cells after damaged liver tissues by the devastating human parasitic flatworm Schistosoma mansoni.

中文翻译:

生化和寄生虫学研究hUCB选择的CD34(+)祖细胞/干细胞在曼氏血吸虫感染小鼠中的作用。

分娩后残留在脐带中​​的胎盘和血液通常可以作为丢弃的组织使用,并且没有任何法律,道德,道德或宗教上的异议,可提供大量的多能CD34(+)祖细胞和干细胞。使用来自人脐带血(hUCB)的离体分离CD34(+)细胞已成为治疗各种疾病(包括外源性病原体感染)的有希望的候选者。我们已经扩展以建立一种合理的方法来研究毁灭性的人类寄生性扁虫曼氏血吸虫对肝脏组织的损伤后CD34(+)细胞的作用。
更新日期:2020-08-21
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