Variety of pathological factors including viral hepatitis, alcohol and drug abuse, metabolic diseases, autoimmune diseases and congenital abnormalities can cause hepatic injury. Liver transplantation is the treatment of choice for end-stage liver diseases, however, it faces several difficulties. So the aim of the work is to evaluate the effect of bone marrow derived mesenchymal stem cells (BM-MSCs) on the liver structure in carbon tetra chloride CCL4 induced liver fibrosis in rats.

中文翻译：

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骨髓间充质干细胞在CCL4诱导的白化大鼠肝纤维化中的作用：组织学和免疫组织化学研究。

各种病理因素，包括病毒性肝炎，酒精和药物滥用，代谢性疾病，自身免疫性疾病和先天性异常，都可能导致肝损伤。肝移植是终末期肝病的首选治疗方法，但是它面临许多困难。因此，本研究的目的是评估骨髓源性间充质干细胞（BM-MSC）对四氯化碳CCL4诱导的大鼠肝纤维化肝脏结构的影响。