Emerging infectious diseases of zoonotic origin are shaping today's infectious disease field more than ever. In this article, we introduce and review three emerging zoonotic viruses. Novel hantaviruses emerged in the Americas in the mid-1990s as the cause of severe respiratory infections, designated hantavirus pulmonary syndrome, with case fatality rates of around 40%. Nipah virus emerged a few years later, causing respiratory infections and encephalitis in Southeast Asia, with case fatality rates ranging from 40% to more than 90%. A new coronavirus emerged in 2012 on the Arabian Peninsula with a clinical syndrome of acute respiratory infections, later designated as Middle East respiratory syndrome (MERS), and an initial case fatality rate of more than 40%. Our current state of knowledge on the pathogenicity of these three severe, emerging viral infections is discussed.

中文翻译：

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流氓呼吸道病毒的诞生和发病机制。


新出现的人畜共患传染病比以往任何时候都更加影响着当今的传染病领域。在本文中，我们介绍并回顾了三种新兴的人畜共患病毒。新型汉坦病毒于 20 世纪 90 年代中期在美洲出现，导致严重呼吸道感染（称为汉坦病毒肺综合征），病死率约为 40%。几年后出现尼帕病毒，在东南亚引起呼吸道感染和脑炎，病死率从40%到90%以上。 2012年，阿拉伯半岛出现了一种新型冠状病毒，表现为急性呼吸道感染临床综合征，后来被命名为中东呼吸综合征（MERS），最初病死率超过40%。讨论了我们目前对这三种严重的新出现的病毒感染的致病性的了解。