Infection and septic complications in burn patients can be monitored by procalcitonin (PCT) and neopterin plasma values. The aim of the study was to investigate serum neopterin and PCT levels with WBC (white blood cell) and CRP (C-reactive protein) levels in patient group (PG) and healthy control group (HCG) and to investigate the relationship of these markers with burn wound infections (BWI). As the PG, 23 patients between 0-12 ages and up to 30% Total Body Surface Area (TBSA) burned and 15 HCG were included. PCT, neopterin, WBC, and CRP results on the first, the seventh, the fourteenth and the 21st day have been compared. During the follow-up period, 11 patients with BWI and 12 patients without BWI were classified as infected and non-infected patients, respectively. PCT and neopterin levels were detected higher in patients with BWI but no significant difference were present. Also, PCT and neopterin levels within the first 24 hours following the burn were detected higher in PG than HCG. CRP and WBC levels were detected high due to burn trauma. PCT and neopterin levels were increased in patients with BWI. PCT levels were increased during the pre-infectious period, while neopterin levels increased during the post-infectious period.

中文翻译：

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血清新蝶呤和降钙素原水平与小儿烧伤创面感染的关系。

烧伤患者的感染和脓毒症并发症可以通过降钙素原（PCT）和新蝶呤血浆值进行监测。本研究的目的是研究患者组（PG）和健康对照组（HCG）的血清新蝶呤和PCT水平与白细胞（WBC）和CRP（C反应蛋白）的水平，并研究这些标志物之间的关系烧伤伤口感染（BWI）。作为PG，包括23例0-12岁至30％的总体表面积（TBSA）烧伤的患者和15例HCG。比较了第一天，第七天，第十四天和第21天的PCT，新蝶呤，WBC和CRP结果。在随访期间，将11例BWI患者和12例BWI患者分别分为感染患者和未感染患者。BWI患者的PCT和新蝶呤水平较高，但无显着差异。同样，在烧伤后的头24小时内，PG中的PCT和新蝶呤水平被检测出高于HCG。由于烧伤，CRP和WBC水平较高。BWI患者的PCT和新蝶呤水平升高。在感染前，PCT水平升高，而在感染后，新蝶呤水平升高。