Enveloped viruses infect host cells by a membrane fusion reaction that takes place at the cell surface or in intracellular compartments following virus uptake. Fusion is mediated by the membrane interactions and conformational changes of specialized virus envelope proteins termed membrane fusion proteins. This article discusses the structures and refolding reactions of specific fusion proteins and the methods for their study and highlights outstanding questions in the field.

中文翻译：

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病毒膜融合蛋白的机制。

包膜病毒通过膜融合反应感染宿主细胞，该膜融合反应在病毒吸收后在细胞表面或细胞内区室发生。融合是由称为膜融合蛋白的专门病毒包膜蛋白的膜相互作用和构象变化介导的。本文讨论了特定融合蛋白的结构和重折叠反应以及它们的研究方法，并突出了该领域的突出问题。