Incomplete intestinal absorption of fructose might lead to abdominal complaints such as pain, flatulence and diarrhoea. Whether defect fructose transporters such as GLUT5 or GLUT2 are involved in the pathogenesis of fructose malabsorption is a matter of debate. The hydrogen production by colonic bacteria is used for diagnosis with the hydrogen breath test. However, the appropriate fructose test dose for correct diagnosis is unclear. Subjects with fructose malabsorption show increased breath hydrogen levels and abdominal symptoms after fructose administration but do not report any symptoms when fructose is given together with glucose. This beneficial effect of glucose, however, cannot be explained yet but might be used for clinical care of these subjects.

中文翻译：

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果糖吸收不良

果糖的肠道吸收不完全可能会导致腹部不适，如疼痛、胀气和腹泻。GLUT5 或 GLUT2 等缺陷果糖转运蛋白是否参与了果糖吸收不良的发病机制是一个有争议的问题。结肠细菌产生的氢气用于氢气呼气试验的诊断。然而，正确诊断的适当果糖测试剂量尚不清楚。果糖吸收不良的受试者在服用果糖后会出现呼吸氢水平升高和腹部症状，但当果糖与葡萄糖一起服用时没有报告任何症状。然而，葡萄糖的这种有益作用尚无法解释，但可用于这些受试者的临床护理。