Tobacco-free electronic cigarettes (e-cigarettes), which are currently not regulated by the FDA, have become widespread as a “safe” form of smoking. One approach to evaluate the potential toxicity of e-cigarettes and other types of potentially “reduced-harm” cigarettes is to compare their emissions of volatile organic compounds (VOCs), including reactive organic electrophilic compounds such as acrolein, and particulate matter to those of conventional and reference cigarettes. Our newly designed fast-flow tube system enabled us to analyze VOC composition and particle number concentration in real-time by promptly diluting puffs of mainstream smoke obtained from different brands of combustion cigarettes and e-cigarettes. A proton transfer reaction time-of-flight mass spectrometer (PTRMS) was used to analyze real-time cigarette VOC emissions with a 1-s time resolution. Particles were detected with a condensation particle counter (CPC). This technique offers real-time analysis of VOCs and particles in each puff without sample aging and does not require any sample pretreatment or extra handling. Several important determining factors in VOC and particle concentration were investigated: (1) puff frequency; (2) puff number; (3) tar content; (4) filter type. Results indicate that electronic cigarettes are not free from acrolein and acetaldehyde emissions and produce comparable particle number concentrations to those of combustion cigarettes, more specifically to the 1R5F reference cigarette. Unlike conventional cigarettes, which emit different amounts of particles and VOCs each puff, there was no significant puff dependence in the e-cigarette emissions. Charcoal filter cigarettes did not fully prevent the emission of acrolein and other VOCs. Copyright 2015 American Association for Aerosol Research

中文翻译：

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电子、潜在降低危害、传统和参考卷烟中 VOC 和颗粒排放的实时快速流管研究

目前不受 FDA 监管的无烟电子烟（e-香烟）已成为一种“安全”的吸烟方式。评估电子烟和其他类型潜在“减害”卷烟的潜在毒性的一种方法是将它们的挥发性有机化合物 (VOC) 的排放量与丙烯醛等活性有机亲电化合物和颗粒物质的排放量进行比较。传统卷烟和参考卷烟。我们新设计的快流管系统使我们能够通过及时稀释从不同品牌的燃烧香烟和电子烟中获得的主流烟雾来实时分析 VOC 成分和颗粒数浓度。质子转移反应飞行时间质谱仪 (PTRMS) 用于分析实时香烟 VOC 排放，时间分辨率为 1 秒。用冷凝粒子计数器（CPC）检测粒子。该技术可实时分析每次抽吸中的 VOC 和颗粒，而无需样品老化，并且不需要任何样品预处理或额外处理。研究了 VOC 和颗粒浓度的几个重要决定因素： (1) 抽吸频率；(2) 粉扑数；(3) 焦油含量；(4)过滤器类型。结果表明，电子烟并非没有丙烯醛和乙醛排放物，并且产生的粒子数浓度与燃烧香烟的粒子数浓度相当，更具体地说，与 1R5F 参考香烟的粒子数浓度相当。与传统香烟不同，每次抽吸会排放不同数量的颗粒和 VOC，因此电子烟排放量没有显着的抽吸依赖性。木炭过滤嘴香烟并不能完全阻止丙烯醛和其他挥发性有机化合物的排放。版权所有 2015 美国气溶胶研究协会