Generation of well-dispersed, well-characterized fibers is important in toxicology studies. A vortex-tube shaking method is investigated using glass fibers to characterize the generated aerosol. Controlling parameters that were studied included initial batch amounts of glass fibers, preparation of the powder (e.g., preshaking), humidity, and airflow rate. Total fiber number concentrations and aerodynamic size distributions were typically measured. The aerosol concentration is only stable for short times (t < 10 min) and then falls precipitously, with concomitant changes in the aerosol aerodynamic size distribution; the plateau concentration and its duration both increase with batch size. Preshaking enhances the initial aerosol concentration and enables the aerosolization of longer fibers. Higher humidity strongly affects the particle size distribution and the number concentration, resulting in a smaller modal diameter and a higher number concentration. Running the vortex shaker at higher flow rates (Q > 0.3 lpm), yields an aerosol with a particle size distribution representative of the batch powder; running the vortex shaker at a lower aerosol flow rate (Q ∼ 0.1 lpm) only aerosolizes the shorter fibers. These results have implications for the use of the vortex shaker as a standard aerosol generator. Copyright 2013 American Association for Aerosol Research

中文翻译：

---

用于雾化纤维的涡旋振荡方法的表征

在毒理学研究中，生成分散良好、表征良好的纤维很重要。使用玻璃纤维来研究涡流管振荡方法来表征生成的气溶胶。所研究的控制参数包括玻璃纤维的初始批次量、粉末的制备（例如，预摇）、湿度和气流速率。通常测量总纤维数浓度和空气动力学尺寸分布。气溶胶浓度仅在短时间内（t < 10 分钟）稳定，然后急剧下降，伴随着气溶胶空气动力学尺寸分布的变化；平台浓度及其持续时间都随着批量大小而增加。预振提高初始气溶胶浓度并使更长的纤维能够气溶胶化。较高的湿度会强烈影响粒度分布和数量浓度，从而导致较小的模态直径和较高的数量浓度。以更高的流速 (Q > 0.3 lpm) 运行涡旋振荡器，产生的气溶胶具有代表批次粉末的粒度分布；以较低的气溶胶流速 (Q ~ 0.1 lpm) 运行涡旋振荡器只会使较短的纤维气溶胶化。这些结果对使用涡旋振荡器作为标准气溶胶发生器有影响。版权所有 2013 美国气溶胶研究协会 以较低的气溶胶流速 (Q ~ 0.1 lpm) 运行涡旋振荡器只会使较短的纤维气溶胶化。这些结果对使用涡旋振荡器作为标准气溶胶发生器有影响。版权所有 2013 美国气溶胶研究协会 以较低的气溶胶流速 (Q ~ 0.1 lpm) 运行涡旋振荡器只会使较短的纤维气溶胶化。这些结果对使用涡旋振荡器作为标准气溶胶发生器有影响。版权所有 2013 美国气溶胶研究协会