Experiments on human and on animal excised specimens as well as in vivo animal preparations are so far the most realistic approaches to simulate the in vivo process of human phonation. These experiments do not have the disadvantage of limited space within the neck and enable studies of the actual organ necessary for phonation, i.e., the larynx. The studies additionally allow the analysis of flow, vocal fold dynamics, and resulting acoustics in relation to well-defined laryngeal alterations.

Purpose of Review: This paper provides an overview of the applications and usefulness of excised (human/animal) specimen and in vivo animal experiments in voice research. These experiments have enabled visualization and analysis of dehydration effects, vocal fold scarring, bifurcation and chaotic vibrations, three-dimensional vibrations, aerodynamic effects, and mucosal wave propagation along the medial surface. Quantitative data will be shown to give an overview of measured laryngeal parameter values. As yet, a full understanding of all existing interactions in voice production has not been achieved, and thus, where possible, we try to indicate areas needing further study.

Recent Findings: A further motivation behind this review is to highlight recent findings and technologies related to the study of vocal fold dynamics and its applications. For example, studies of interactions between vocal tract airflow and generation of acoustics have recently shown that airflow superior to the glottis is governed by not only vocal fold dynamics but also by subglottal and supraglottal structures. In addition, promising new methods to investigate kinematics and dynamics have been reported recently, including dynamic optical coherence tomography, X-ray stroboscopy and three-dimensional reconstruction with laser projection systems. Finally, we touch on the relevance of vocal fold dynamics to clinical laryngology and to clinically-oriented research.

迄今为止，对人类和动物切除的标本以及体内动物制剂进行的实验是模拟人类发声的体内过程的最现实方法。这些实验没有颈部空间有限的缺点，并且可以研究发声所必需的实际器官，即喉部。这些研究还允许分析与明确定义的喉部改变有关的血流，声带动力学以及所产生的声音。

审查目的：本文概述了切除的（人/动物）标本和体内动物实验在语音研究中的应用和有用性。这些实验使可视化和分析了脱水效应，声带疤痕，分叉和混沌振动，三维振动，空气动力效应以及沿内表面的粘膜波传播。将显示定量数据，以概述测量的喉参数值。到目前为止，还没有完全了解语音生产中所有现有的交互作用，因此，在可能的情况下，我们尝试指出需要进一步研究的领域。

最新发现：这篇评论背后的另一个动机是强调与声带动力学及其应用研究有关的最新发现和技术。例如，最近对声道气流与声音产生之间相互作用的研究表明，优于声门的气流不仅受声带动力学的影响，而且受声门下和声门上结构的支配。另外，最近已经报道了研究运动学和动力学的有前途的新方法，包括动态光学相干断层扫描，X射线频闪检查和激光投影系统的三维重建。最后，我们探讨了声带动力学与临床喉科学和以临床为导向的研究的相关性。