BackgroundFanconi anemia is one of the best studied inherited cancer-prone diseases. Greatly improved protocols for hematopoietic stem cell transplantation increasingly save the lives of these young patients. However, in both transplanted and not transplanted patients, the emergence of aggressive squamous cell carcinoma represents a major medical challenge.ConclusionsThis mini review summarizes current knowledge about the pathogenesis of squamous cell carcinoma (SCC) in the special context of Fanconi anemia.

中文翻译：

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范可尼贫血：鳞状细胞癌高危年轻患者

背景范可尼贫血是研究得最好的遗传性易患癌症的疾病之一。极大改进的造血干细胞移植方案越来越多地挽救了这些年轻患者的生命。然而，在移植和未移植患者中，侵袭性鳞状细胞癌的出现代表了一项重大的医学挑战。结论这篇小型综述总结了在范可尼贫血特殊背景下鳞状细胞癌 (SCC) 发病机制的最新知识。