Matrix metalloproteinases are vital drivers of synaptic remodeling in health and disease. It is suggested that at early stages of epileptogenesis, inhibition of matrix metalloproteinases may help ameliorate cell death, aberrant network rewiring, and neuroinflammation and prevent development of epilepsy.

中文翻译：

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基质金属蛋白酶和癫痫发生

基质金属蛋白酶是健康和疾病中突触重塑的重要驱动因素。有人提出，在癫痫发生的早期阶段，基质金属蛋白酶的抑制可能有助于改善细胞死亡、异常的网络重新布线和神经炎症，并防止癫痫的发展。