The nucleosome serves as a general gene repressor by the occlusion of regulatory and promoter DNA sequences. Repression is relieved by the SWI/SNF-RSC family of chromatin-remodeling complexes. Research reviewed here has revealed the essential features of the remodeling process.

中文翻译：

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染色质重塑和转录的启动

核小体通过封闭调节和启动子 DNA 序列作为一般基因阻遏物。SWI/SNF-RSC 家族的染色质重塑复合物缓解了抑制。这里回顾的研究揭示了重塑过程的基本特征。