Danger molecules are the first signals released from dying tissue after stroke. These danger signals bind to receptors on immune cells that will result in their activation and the release of inflammatory and neurotoxic mediators, resulting in amplification of the immune response and subsequent enlargement of the damaged brain volume. The release of danger signals is a central event that leads to a multitude of signals and cascades in the affected and neighbouring tissue, therefore providing a potential target for therapy.

中文翻译：

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中风危险信号。

危险分子是中风后垂死组织释放的第一批信号。这些危险信号与免疫细胞上的受体结合，从而导致它们的活化以及炎性和神经毒性介质的释放，从而导致免疫反应的放大和受损大脑体积的扩大。危险信号的释放是一个中心事件，在受影响的组织和邻近组织中导致大量信号和级联反应，因此提供了潜在的治疗靶标。