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Biosynthesis of silver nanoparticles using the extract of Alternanthera sessilis-antiproliferative effect against prostate cancer cells.
Cancer Nanotechnology ( IF 4.5 ) Pub Date : 2013-09-15 , DOI: 10.1007/s12645-013-0045-4
M Jannathul Firdhouse 1 , P Lalitha 1
Affiliation  

Green synthesis of silver nanoparticles was carried out using the aqueous extract of Alternanthera sessilis under various experimental conditions. The aqueous extract of Alternanthera sessilis showed significant potential for the quick reduction of silver ions. The synthesized silver nanoparticles were characterized with UV-visible absorption spectrophotometer, XRD, SEM, and FTIR analysis. The average crystallite size as calculated from x-ray diffraction studies and SEM analysis was found to be less than 100 nm. The cytotoxic activity of synthesized nanosilver was carried out against prostate cancer cells (PC3) by MTT assay and found to show significant activity. The present work of biosynthesis of silver nanoparticles using Alternanthera sessilis appears to be cost effective, eco-friendly, and an alternative to conventional method of synthesis.

中文翻译:

银杏叶提取物的生物合成银纳米粒子对前列腺癌细胞的抗增殖作用。

在不同的实验条件下,使用七叶莲的水提取物进行银纳米粒子的绿色合成。七叶莲的水提取物显示出快速还原银离子的巨大潜力。用紫外可见吸收分光光度计,XRD,SEM和FTIR分析对合成的银纳米颗粒进行表征。由X射线衍射研究和SEM分析计算出的平均微晶尺寸小于100nm。通过MTT测定法,合成的纳米银对前列腺癌细胞(PC3)具有细胞毒活性,并显示出显着的活性。使用芝麻亚瑟银(Alternanthera sessilis)生物合成银纳米颗粒的当前工作似乎是成本有效,生态友好的,并且是常规合成方法的替代方法。
更新日期:2013-09-15
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