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Surface plasmon-enhanced Ag/CuS nanocomposites for cancer treatment.
Cancer Nanotechnology ( IF 4.5 ) Pub Date : 2013-05-18 , DOI: 10.1007/s12645-013-0039-2
Chang Yang 1 , Lun Ma 2 , Xiaoju Zou 2 , Guangya Xiang 3 , Wei Chen 2
Affiliation  

Photothermal therapy (PTT) for cancer treatment is the use of heat between 41 and 45 °C to damage cancer cells. As a new type of transducer agent for PTT of cancer, CuS nanoparticles have several advantages. The most favorable features are the low cost, simple, and easy preparation and small size for targeting. However, the CuS nanoparticle PTT efficacy needs to be improved for practical applications. In this study, the CuS nano-PTT efficiency is enhanced via the local field enhancement from Ag nanoparticle surface plasmon coupling. The results show that absorbance of CuS nanoparticles in Ag/CuS nanocomposites is enhanced about four times by Ag nanoparticle surface plasmon coupling. Consequently, the PTT efficacy is enhanced and a power of 0.6 W/cm2 with a 980-nm laser is sufficient for Ag/CuS nano-PTT activation for cancer treatment in vitro observations.

中文翻译:

表面等离子体增强的Ag / CuS纳米复合材料用于癌症治疗。

用于癌症治疗的光热疗法(PTT)是利用41至45°C之间的热量来破坏癌细胞。作为一种新型的癌症PTT换能剂,CuS纳米粒子具有许多优势。最有利的功能是低成本,简单易行的准备以及较小的目标尺寸。但是,对于实际应用,需要提高CuS纳米颗粒PTT的功效。在这项研究中,通过银纳米粒子表面等离子体激元耦合的局部场增强来提高CuS纳米PTT效率。结果表明,Ag / CuS纳米复合材料中CuS纳米颗粒的吸收通过Ag纳米颗粒表面等离子体激元耦合而提高了约4倍。因此,增强了PTT功效,并且功效为0。
更新日期:2013-05-18
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