Reported herein is the development of non-covalent, proximity-induced energy transfer from small-molecule toxicants to organic fluorophores bound in the cavity of γ-cyclodextrin. This energy transfer occurs with exceptional efficiency for a broad range of toxicants in complex biological media, and is largely independent of the spectral overlap between the donor and acceptor. This generally applicable phenomenon has significant potential in the development of new turn-on detection schemes.

中文翻译：

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用于广泛适用的小分子检测的环糊精促进的能量转移

本文报道了从小分子毒物到结合在 γ-环糊精腔中的有机荧光团的非共价、邻近诱导的能量转移的发展。这种能量转移对于复杂生物介质中的多种毒物以优异的效率发生，并且在很大程度上独立于供体和受体之间的光谱重叠。这种普遍适用的现象在开发新的开启检测方案方面具有巨大的潜力。