Three binuclear Co(III)-salen complexes have been synthesized based on a series of hydrophilic cyclic frameworks with different ring sizes. The catalytic performance of Co-salen complexes have further been evaluated in the hydrolytic kinetic resolution of racemic epoxides. And kinetic studies reveal that the binuclear Co-salen catalysts show a higher reactivity and better enantioselectivity in comparison to monometallic reference complex, indicating the two Co-salen units on the cyclic framework may work in a cooperative manner. Specifically, Co3, with the most flexible cyclic framework exhibits the best catalytic performance among the three catalysts, due to the efficient cooperative interactions between two cobalt centers.

基于一系列具有不同环尺寸的亲水性环状骨架，合成了三种双核Co（III）-salen配合物。在外消旋环氧化物的水解动力学拆分中，还对Co-salen配合物的催化性能进行了评估。动力学研究表明，双核Co-salen催化剂与单金属参考配合物相比具有更高的反应性和更好的对映选择性，表明环状骨架上的两个Co-salen单元可能以协同方式起作用。具体而言，由于两个钴中心之间的有效协同相互作用，具有最灵活的环状骨架的Co3在三种催化剂中均表现出最佳的催化性能。